A lieu le
04 juillet 2013 à partir de 13h30
jusqu'au
05 juillet 2013 à 16h00
This symposium has for main objective to discuss the many ways by which transcription and RNA processing can interfere with genome stability and promote cancer development. In particular, will be discussed the mechanisms used by cells to circumvent and/or repair transcription-associated obstacles to DNA replication.
Registrations are closed
Scientific program
THURSDAY JULY 4 |
|
13:30 |
Attendees Welcome |
14:10 |
♦ LECTURE - Chromatin structure as a mediator of transcription- and R-loop- associated recombination, Andres AGUILERA (CABIMER, Sevilla) |
14:45 |
• Transcriptionally active chromatin channels DNA double-strand breaks to RAD51-dependent repair, Gaelle LEGUBE (LBCMCP, Toulouse) |
16h00 |
Break |
SESSION 2 : RNA PROCESSING AND R-LOOPS |
|
17:00 |
♦ LECTURE - Widespread R-loop formation in human genes, Frederic CHEDIN (UC Davis) |
17:35 |
• Specific RNA processing factors influence mitotic chromosome organization by modulating the recruitment of the Condensin complex, Vincent VANOOSTHUYSE (ENS, Lyon) |
18:25 |
♦ LECTURE - RNAi and Cenp-B coordinate DNA replication and epigenetic modification in heterochromatin, Rob MARTIENSSEN (Cold Spring Harbor) |
19:00 |
Buffet - Genopolys |
FRIDAY JULY 5 |
|
SESSION 3 : DNA REPLICATION |
|
09:00 |
♦ LECTURE - The lysine specific demethylases, Lsd1/2, are required for replication fork pauses and asymmetric cell division, Benoit ARCANGIOLI (Pasteur, Paris) |
09:35 |
• Replisome surveillance by Fanconi anemia proteins and their interacting partners, Angelos CONSTANTINOU (IGH, Montpellier) |
10h50 | Break |
SESSION 4 : RNA PROCESSING AND CANCER |
|
11:20 |
♦ LECTURE - Deciphering Splicing regulators of tissue-specific splicing in both normal and cancer tissues, Jamal TAZI (IGMM, Montpellier) |
11:55 |
• Beyond the RNA: the role of epigenetics in alternative splicing regulation, Reini LUCO (IGH, Montpellier) |
12h45 | LUNCH |
SESSION 5 : GENOME INSTABILITY |
|
14:00 |
♦ LECTURE - RNA Processing Defects and Genome Instability, Karlene CIMPRICH (Stanford) |
14:35 |
• ELL, a new partner of TFIIH, plays a role in transcription restart after DNA repair, Ambra GIGLIA-MARI (IPBS, Toulouse) |
15:25 |
Enf of the mini-symposium |
Your Venue - Warning
The "Tour de France" will be arriving in Montpellier on 4/07 and leaving on 5/07, causing potential traffic disruptions.
You will find below : a list of hotels and Genopolys' access map.