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Scientific Program

 

Scientific program

 

Wednesday 20nd November
13:45-14:00 Opening ceremony
14:00-16:00 Translational research: from biology to clinics
16:00-17:00 Poster session (1)
17:00-18:30       
Post-translational modifications and cancer   Education thérapeutique   Health technologies
18:30-19:30 Drinks & Posters
20:30-23:00 Speaker and moderator dinner, under invitation

 

Thursday 21st November
8:30-10:00 Mechanical constraints in oncological processes   Recherche interventionnelle (1)
10:00-11:00 Poster session (2)
11:00-12:45 Chemical biology and cancer   Recherche interventionnelle (2)
12:45-14:15 Lunch
14:15-15:45      
Genome dynamics and cancer   Translational Research   Ethique et prévention: aspects individuels et collectifs
15:45-16:45 Break
16:45-18:15 Translational research: from biology to surgery
18:15-19:00 Ethics in cancer research
20:00 Departure for Gala dinner, social event

 

Friday 22nd November
08:30-10:15      
Microenvironment & Invasion   Mathematical modeling for therapy response prediction
10:15-11:00 Break
11:00-12:30 Research in thoracic oncology
12:30-12:45 Poster Awards - Closing ceremony
12:45-14:00 Lunch

 

 

Wednesday 20nd November

13:45 - 14:00 : Opening ceremony

Muriel MATHONNET, Scientific director of Cancéropôle Grand Sud-Ouest

14:00 - 16:00 : Plenary session

  • Translational research: from biology to clinics
    Chairs: Julie PANNEQUIN and Majid KHATIB
    • KEYNOTE SPEAKER: Thomas HELLEDAY, The University of Sheffield, Department of Oncology & Metabolism, The Medical School (United Kingdom) - Targeting DNA repair: from basic biology to clinical trials
    • (Not) lost in translation: gene therapy for pancreatic cancer - Pierre CORDELIER, Cancer Research Center of Toulouse
    • Smart-devices for the detection of circulating cancer biomarkers in clinical routine - Aline CERF, LAAS-CNRS (Toulouse)
    • Mass spectrometry in clinical practice using hepatocellular adenomas as a proof of concept - Frederic SALTEL, Bordeaux Research in Translational Oncology
    • Glycosylation and cancer: the phostines window - Norbert BAKALARA, Institute for Neurosciences of Montpellier

 

17:00 - 18:30 : Parallel sessions organized by Cancéropôle GSO Axes

  • Post-translational modifications and cancer / Axis 1 Axis 2 session
    Chairs: Olivier COUX
    • KEYNOTE SPEAKER: Sylvie URBEInstitute of Translational Medicine, University of Liverpool (United Kingdom) - Deubiquitylases (DUBs): druggable regulators of protein and organelle homeostasis
    • Targeting the ubiquitin-like molecule Nedd8 for therapeutic intervention - Dimitris XIRODIMASCenter for Biochemical and Macromolecular Research (Montpellier)
    • Hydrogen sulfide (H2S) signals through protein persulfidation - Milos FILIPOVIC, Cellular Biochemistry and Genetics Institute (Bordeaux)
    • 1 selected communication

 

  • Education thérapeutique / session Axe 4
    Modération: Florence SORDES
    • ORATEUR INVITE: Sandrine ROUSSELUniversité Catholique de Louvain (Belgique)
    • Programme ETP "GYN and Co LR": Evaluation d'une prise en charge précoce des troubles sexuels et fonctionnels pelviens chez les patientes traitées par curiethérapie utérovaginale ou intravaginale - Anne STOEBNER, Département des soins de support, ICM (Montpellier)
    • 2 communications sélectionnées

 

  • Health technologies / Axis 5 session
    Chairs: Anne-Marie GUE
    • EMERGENT PROJECTS
      • Frédéric FRISCOURT, European Institute of Chemistry and Biology (Bordeaux) - Towards the Selective Tagging of the Sialome for Imaging Cancer Cells - A Chemical Biology Tale
      • Véronique GIGOUX, Laboratory of Physics and Chemistry of Nano-Objects (Toulouse) - Targeted magnetic nanoparticles remotely induced mechanical destruction of tumor microenvironment through rotating magnetic field
    • 5 selected talks for "Ma techno en 180 secondes" (flash posters toutes technologies)

 

 

Thursday 21st November

08:30 - 10:00 : Plenary session and session Axe 4

  • Mechanical constraints in oncological processes 
    Chairs:
    • KEYNOTE SPEAKER: Matthieu PIEL, Curie Institute (Paris) - Causes and consequences of large deformations of the cell nucleus: from migrating immune cells to breast duct carcinoma in situ
    • A new way to escape: how structural centrosome aberrations promote invasive behaviors of epithelial cells - Olivier GANIER, Institute of Human Genetics (Montpellier)
    • Making, watching and stressing tumor organoids in 3D - Pierre NASSOY, Photonics, Numeric and Nanosciences Laboratory & Institut Optique Graduate School (Bordeaux)
    • 1 selected communication

 

  • Recherche interventionnelle (1)
    Modération: Louise POTVIN
    • ORATRICE INVITEE: Louise POTVIN, École de santé publique, Université de Montréal, (Canada) - La recherche interventionnelle: science des solutions.
    • Table-ronde : Linda Cambon (Bordeaux Population Health, Bordeaux), Florence Cousson-Gélie (département Epidaure et laboratoire Epsylon, Montpellier)Cyrille Delpierre (EQUITY: Embodiment, social ineQualities, lifecoUrse epidemiology, cancer and chronIc diseases, intervenTions, methodologY, Toulouse), Pierre Ingrand (CIC 14.02, Poitiers), Grégory Ninot (plateforme CEPS, Montpellier)Philippe Terral (CRESCO: Centre de recherches sciences sociales sports et corps , Toulouse)

 

11:00 - 12:45 : Plenary session and session Axe 4

  • Chemical biology and cancer 
    Chair: Sébastien BRITTON
    • KEYNOTE SPEAKER: Raphaël RODRIGUEZ, Curie Institute (Paris) - Prevalent roles of iron in cancer
    • Stapled Peptides and Foldamers as Tools for Therapeutic Innovation - Muriel AMBLARD, Max Mousseron Biomolecules Institute (Montpellier)
    • Programming molecules for cancer therapy - Sébastien PAPOT, Institute of Chemistry of Materials and Media of Poitiers
    • 2 selected communications

 

  • Recherche interventionnelle (2)
    Modération: Florence COUSSON-GELIE
    • ORATRICE INVITEE: Julie GAILLOT DE SAINTIGNON, Institut National du Cancer (Paris)
    • 3 communications sélectionnées

 

14:15 - 15:45 : Parallel sessions organized by Cancéropôle GSO Axes

  • Genome dynamics and cancer / Axis 2 session
    Chair: Malik LUTZMANN
    • KEYNOTE SPEAKER: Raphaël CECCALDI, Curie Institute (Paris) - How BRCA-deficient tumors ensure DNA replication and repair
    • New synthetic lethality approaches targeting DNA safeguard pathways and the mitochondrial step of nucleotide neosynthesis (pyrimidine) in breast cancer - Stéphanie ARNOULD, Cancer Research Institute of Montpellier 
    • Generation of cells resistant to tyrosine kinase inhibitors in chronic myeloid leukemia by a genome editing technique - François-Xavier MAHON, CLCC Bordeaux & UMR1218 ACTION
    • 1 selected communication

 

  • Translational Research, from biology to clinics / Axis 3 session
    Modération: Majid KHATIB
    • Targeting Apelin cleavage sites for colorectal cancer treatment - Géraldine SIEGFRIED, Angiogenesis and Cancer Microenvironment Laboratory - ACML (Bordeaux)
    • EMERGENT PROJECTS :
      • Resistance of Melanoma to Immune Checkpoint Inhibitors is Overcome by Targeting the Sphingosine Kinase 1 - Céline COLACIOS, Toulouse Cancer Research Centre
      • Elise DELUCHELimoges University Hospital
    • API-K PROJECTS : 2 selected speakers
    • FLASH POSTERS : 2 selected speakers

 

  • Ethique et prévention: aspects individuels et collectifs / session Axe 4
    Modération: Annie SASCO
    • Orateur invité: Emmanuelle RIAL SEBBAG, BIOETHICS - BIOethics Exploring Trajectories of Health Innovations Challenging Society (Toulouse)
    • Table-ronde: Silviane Darquy, Bordeaux population health, 
    • 1 intervenant sur communication sélectionnée

 

16:45 - 18:15 : Plenary session

  • Translational research: from biology to surgery 
    Chair: Muriel MATHONNET
     
    • KEYNOTE SPEAKER: Patrick PESSAUXUniversity Hospital Institute (Strasbourg) - Planification-simulation-navigation: toward a precise surgery
    • Digital innovations in liver surgery - Eric VIBERT, APHP - Paul Brousse Hospital (Villejuif)
    • François QUENET, Montpellier Cancer Institute
    • Françoise CAILLER, SurgiMab (Montpellier)

 

18:15 - 19:00 : Plenary session

  • Ethics in cancer research 
    Chair:  

    • KEYNOTE SPEAKER: Hervé CHNEIWEISS, Inserm Ethics Committee President & Hed of the Neuroscience Department (Paris) - What are the current challenging ethical issues in oncology research ?

 

Friday 22nd November

 

08:30 - 10:15 : Parallel sessions organized by Cancéropôle GSO Axes

  • Microenvironment & Invasion / Axis 1 session
    Chair: Violaine MOREAU
    • KEYNOTE SPEAKER: Martin HUMPHRIES, Wellcome Center for Cell-Matrix Research, University of Manchester (UK) - Mechanisms of extracellular rigidity sensing via the adhesion nexus
    • Glioblastoma metabolism and microenvironment: putting tumor back in context - Thomas DAUBON, Angiogenesis and Cancer Microenvironment Laboratory - ACML (Bordeaux)
    • Mechanosensitive TRP channels push cancer cells invasion and metastasis formation - Aubin PENNA, Signalisation and Membrane Ionic Transports Laboratory - STIM (Poitiers)
    • 2 selected communications

 

  • Mathematical modeling for therapy response prediction / Axis 3 & Axis 5 session
    Chairs: Romain LARIVE, Majid KHATIB & Anne-Marie GUE 

    • KEYNOTE SPEAKER: Rosa Hernansaiz Ballesteros, Institute for Computational Biomedicine (Heidelberg, Germany)
    • Early evaluation of cancer treatments using modeling and AI - Olivier SAUT, Institute for Research in Computer Science and Automation (Bordeaux)
    • Tumor microenvironment cellular network inference and analysis from bulk and single cell transcriptomes - Jacques COLINGE, Cancer Research Institute of Montpellier
    • Radio-genomics approach for therapy response prediction - Thierry COLIN, Sophia Genetics (Bordeaux)
    • 1 selected communication

 

11:00 - 12:30: Plenary Session

  • Research in thoracic oncology
    Chair: David SANTAMARIA 

    • KEYNOTE SPEAKER: Mariano BARBACID, Spanish National Cancer Research Center - CNIO (Madrid, Spain) - Targeting K-RAS mutant lung tumors: an unmet medical need
    • Understanding and overcoming resistance to targeted therapy in lung cancer - Julien MAZIERES, Toulouse Oncopole Cancer University Institute - IUCT-O (Toulouse)
    • Role of the Notch pathway in lung adenocarcinoma: beyond the KrasG12V mouse model - Antonio MARAVER, Cancer Research Institute of Montpellier
    • 1 selected communication